Mitochondrial MI sCU es in liver regeneration
نویسندگان
چکیده
منابع مشابه
Mitochondrial Regeneration in Liver Cells
Hepatic cells contain, besides well defined organelles--mitochondria, ergastoplasm, and Golgi appara tus-round or ovular structures which recall the "microbodies" described by Rhodin (1) in the brush border kidney cells of the mouse. This work aims to define these organelles, to s tudy their behavior under various experimental conditions and their relation to mitochondria. Ra t liver, either no...
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The cytoplasm of the hepatic cell contains, besides the well known organelles, microbodies, characterized by a single membrane, a finely granular matrix, and average dimensions below those of mitochondria. Microbodies, rare in normal cells, become more numerous in regenerative livers and in various pathological conditions. In these cases, they either evolve towards degenerative forms or else sh...
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BACKGROUND & OBJECTIVES It has been reported that some proteins are released from mitochondria during liver regeneration after partial hepatectomy (PH), but the relationship between proteins release and mitochondrial permeability transition (MPT) remains unclear. We undertook this study to demonstrate the changes of mitochondrial ultrastructure and proteins release during liver regeneration and...
متن کاملLack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.
The liver has an exceptional replicative capacity following partial hepatectomy or chemical injuries. Cellular proliferation requires increased production of energy and essential metabolites, which critically depend on the mitochondria. To determine whether Top1mt, the vertebrate mitochondrial topoisomerase, is involved in this process, we studied liver regeneration after carbon tetrachloride (...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2016
ISSN: 0270-9139
DOI: 10.1002/hep.28816